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| Value | Buffalo | Stat | San Diego | Value |
|---|---|---|---|---|
| 401.8 | 71 | Total Offense | 57 | 422 |
| 171.9 | 66 | Rushing Offense | 74 | 159.8 |
| 229.9 | 67 | Passing Offense | 35 | 262.3 |
| 131.4 | 60 | Team Passing Efficiency | 81 | 124.12 |
| 30.8 | T-57 | Scoring Offense | 70 | 28.2 |
| 376.3 | 43 | Total Defense | 55 | 392.6 |
| 159.8 | 58 | Rushing Defense | 22 | 132.9 |
| 216.6 | 37 | Passing Yards Allowed | 103 | 259.7 |
| 118.06 | 31 | Team Passing Efficiency Defense | 89 | 136.36 |
| 22.3 | T-27 | Scoring Defense | 96 | 32.3 |
| 1.3 | 4 | Turnover Margin | T-118 | -1 |
| 0.406 | 58 | 3rd Down Conversion Pct | 60 | 0.401 |
| 0.467 | T-70 | 4th Down Conversion Pct | 87 | 0.429 |
| 0.335 | 18 | 3rd Down Conversion Pct Defense | 60 | 0.391 |
| 0.267 | 3 | 4th Down Conversion Pct Defense | 44 | 0.455 |
| 0.867 | T-35 | Red Zone Offense | 117 | 0.717 |
| 0.722 | 10 | Red Zone Defense | 123 | 0.951 |
| 36.36 | 80 | Net Punting | 75 | 36.46 |
| 5.78 | 96 | Punt Returns | 33 | 11 |
| 22.3 | 45 | Kickoff Returns | 63 | 21.3 |
| 256 | 63 | First Downs Offense | 73 | 247 |
| 224 | 24 | First Downs Defense | 53 | 246 |
| 5.75 | T-68 | Fewest Penalties Per Game | 86 | 6.25 |
| 62 | 106 | Fewest Penalty Yards Per Game | 89 | 53.83 |
| 31:52 | 28 | Time of Possession | 22 | 32:0 |